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miR-17–92 explains MYC oncogene addiction

MYC regulates tumorigenesis by coordinating the expression of thousands of genes. We found that MYC appears to regulate the decisions between cell survival versus death and self-renewal versus senescence through the microRNA miR-17–92 cluster. Addiction to the MYC oncogene may therefore in fact be a...

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Detalhes bibliográficos
Publicado no:Mol Cell Oncol
Main Authors: Li, Yulin, Casey, Stephanie C, Choi, Peter S, Felsher, Dean W
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4905255/
https://ncbi.nlm.nih.gov/pubmed/27308380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/23723548.2014.970092
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