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miR-19 is a key oncogenic component of mir-17-92

Recent studies have revealed the importance of multiple microRNAs (miRNAs) in promoting tumorigenesis, among which mir-17-92/Oncomir-1 exhibits potent oncogenic activity. Genomic amplification and elevated expression of mir-17-92 occur in several human B-cell lymphomas, and enforced mir-17-92 expres...

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Detalhes bibliográficos
Main Authors: Olive, Virginie, Bennett, Margaux J., Walker, James C., Ma, Cong, Jiang, Iris, Cordon-Cardo, Carlos, Li, Qi-Jing, Lowe, Scott W., Hannon, Gregory J., He, Lin
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2800084/
https://ncbi.nlm.nih.gov/pubmed/20008935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1861409
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