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miR-17–92 explains MYC oncogene addiction

MYC regulates tumorigenesis by coordinating the expression of thousands of genes. We found that MYC appears to regulate the decisions between cell survival versus death and self-renewal versus senescence through the microRNA miR-17–92 cluster. Addiction to the MYC oncogene may therefore in fact be a...

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Publicat a:Mol Cell Oncol
Autors principals: Li, Yulin, Casey, Stephanie C, Choi, Peter S, Felsher, Dean W
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4905255/
https://ncbi.nlm.nih.gov/pubmed/27308380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/23723548.2014.970092
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