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MYC Inactivation Elicits Oncogene Addiction through Both Tumor Cell–Intrinsic and Host-Dependent Mechanisms
Tumorigenesis is generally caused by genetic changes that activate oncogenes or inactivate tumor suppressor genes. The targeted inactivation of oncogenes can be associated with tumor regression through the phenomenon of oncogene addiction. One of the most common oncogenic events in human cancer is t...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
SAGE Publications
2010
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2965623/ https://ncbi.nlm.nih.gov/pubmed/21037952 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1947601910377798 |
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