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MYC Inactivation Elicits Oncogene Addiction through Both Tumor Cell–Intrinsic and Host-Dependent Mechanisms

Tumorigenesis is generally caused by genetic changes that activate oncogenes or inactivate tumor suppressor genes. The targeted inactivation of oncogenes can be associated with tumor regression through the phenomenon of oncogene addiction. One of the most common oncogenic events in human cancer is t...

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Detalhes bibliográficos
Autor principal: Felsher, Dean W.
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2965623/
https://ncbi.nlm.nih.gov/pubmed/21037952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1947601910377798
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