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A Tumor-Immune Mathematical Model of CD4+ T Helper Cell Dependent Tumor Regression by Oncogene Inactivation

Understanding the complex dynamics between the tumor cells and the host immune system will be key to improved therapeutic strategies against cancer. We propose an ODE-based mathematical model of both the tumor and immune system and how they respond to inactivation of the driving oncogene. Our model...

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Detalhes bibliográficos
Publicado no:Conf Proc IEEE Eng Med Biol Soc
Main Authors: Nwabugwu, Chinyere I., Rahra, Kavya, Felsher, Dean W., Paik, David S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4487533/
https://ncbi.nlm.nih.gov/pubmed/24110741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1109/EMBC.2013.6610554
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