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An Essential Role for the Immune System in the Mechanism of Tumor Regression Following Targeted Oncogene Inactivation

Tumors are genetically complex and can have a multitude of mutations. Consequently, it is surprising that the suppression of a single oncogene can result in rapid and sustained tumor regression, illustrating the concept that cancers are often “oncogene addicted.” The mechanism of oncogene addiction...

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Autors principals: Casey, Stephanie C., Li, Yulin, Felsher, Dean W.
Format: Artigo
Idioma:Inglês
Publicat: 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4201505/
https://ncbi.nlm.nih.gov/pubmed/24791942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12026-014-8503-6
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