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Oncogene withdrawal engages the immune system to induce sustained cancer regression

The targeted inactivation of a single oncogene can induce dramatic tumor regression, suggesting that cancers are “oncogene addicted.” Tumor regression following oncogene inactivation has been thought to be a consequence of restoration of normal physiological programs that induce proliferative arrest...

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Autori principali: Casey, Stephanie C, Li, Yulin, Fan, Alice C, Felsher, Dean W
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4118610/
https://ncbi.nlm.nih.gov/pubmed/25089198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2051-1426-2-24
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