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A mathematical model of tumor regression and recurrence after therapeutic oncogene inactivation

The targeted inactivation of individual oncogenes can elicit regression of cancers through a phenomenon called oncogene addiction. Oncogene addiction is mediated by cell-autonomous and immune-dependent mechanisms. Therapeutic resistance to oncogene inactivation leads to recurrence but can be counter...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Sci Rep
Päätekijät: Hori, Sharon S., Tong, Ling, Swaminathan, Srividya, Liebersbach, Mariola, Wang, Jingjing, Gambhir, Sanjiv S., Felsher, Dean W.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2021
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7809285/
https://ncbi.nlm.nih.gov/pubmed/33446671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-78947-2
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