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A Tumor-Immune Mathematical Model of CD4+ T Helper Cell Dependent Tumor Regression by Oncogene Inactivation

Understanding the complex dynamics between the tumor cells and the host immune system will be key to improved therapeutic strategies against cancer. We propose an ODE-based mathematical model of both the tumor and immune system and how they respond to inactivation of the driving oncogene. Our model...

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Dettagli Bibliografici
Pubblicato in:Conf Proc IEEE Eng Med Biol Soc
Autori principali: Nwabugwu, Chinyere I., Rahra, Kavya, Felsher, Dean W., Paik, David S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4487533/
https://ncbi.nlm.nih.gov/pubmed/24110741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1109/EMBC.2013.6610554
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