Survival and Death Signals Can Be Used to Predict when Oncogene Inactivation Will Elicit Oncogene Addiction

Cancers can exhibit dramatic tumor regression following oncogene inhibition through the phenomenon of “oncogene addiction”. The ability to predict when a tumor will exhibit oncogene addiction would be useful in the development of targeted therapeutics. Oncogene addiction is likely the consequence of...

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Main Authors: Tran, Phuoc T., Bendapudi, Pavan K., Lin, H. Jill, Choi, Peter, Koh, Shan, Chen, Joy, Horng, George, Hughes, Nicholas P., Schwartz, Lawrence H., Miller, Vincent A., Kawashima, Toshiyuki, Kitamura, Toshio, Paik, David, Felsher, Dean W.
Formato: Artigo
Idioma:Inglês
Publicado: 2011
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3966995/
https://ncbi.nlm.nih.gov/pubmed/21974937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3002018
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