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High throughput automated chromatin immunoprecipitation as a platform for drug screening and antibody validation(,)

Chromatin immunoprecipitation (ChIP) is an assay for interrogating protein–DNA interactions that is increasingly being used for drug target discovery and screening applications. Currently the complexity of the protocol and the amount of hands-on time required for this assay limits its use to low thr...

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Detalhes bibliográficos
Main Authors: Wu, Angela R., Kawahara, Tiara L.A., Rapicavoli, Nicole A., van Riggelen, Jan, Shroff, Emelyn H., Xu, Liwen, Felsher, Dean W., Chang, Howard Y., Quake, Stephen R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4117344/
https://ncbi.nlm.nih.gov/pubmed/22566096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c2lc21290k
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