High throughput automated chromatin immunoprecipitation as a platform for drug screening and antibody validation(,)

Chromatin immunoprecipitation (ChIP) is an assay for interrogating protein–DNA interactions that is increasingly being used for drug target discovery and screening applications. Currently the complexity of the protocol and the amount of hands-on time required for this assay limits its use to low thr...

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Autori principali: Wu, Angela R., Kawahara, Tiara L.A., Rapicavoli, Nicole A., van Riggelen, Jan, Shroff, Emelyn H., Xu, Liwen, Felsher, Dean W., Chang, Howard Y., Quake, Stephen R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4117344/
https://ncbi.nlm.nih.gov/pubmed/22566096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c2lc21290k
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