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High throughput automated chromatin immunoprecipitation as a platform for drug screening and antibody validation(,)

Chromatin immunoprecipitation (ChIP) is an assay for interrogating protein–DNA interactions that is increasingly being used for drug target discovery and screening applications. Currently the complexity of the protocol and the amount of hands-on time required for this assay limits its use to low thr...

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Main Authors: Wu, Angela R., Kawahara, Tiara L.A., Rapicavoli, Nicole A., van Riggelen, Jan, Shroff, Emelyn H., Xu, Liwen, Felsher, Dean W., Chang, Howard Y., Quake, Stephen R.
格式: Artigo
語言:Inglês
出版: 2012
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4117344/
https://ncbi.nlm.nih.gov/pubmed/22566096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c2lc21290k
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