Opposing Actions of Heat Shock Protein 90 and 70 Regulate Nicotinamide Adenine Dinucleotide Phosphate Oxidase Stability and Reactive Oxygen Species Production

OBJECTIVE: Excessive reactive oxygen species contribute to vascular dysfunction. We have previously shown that heat shock protein (Hsp90) inhibitors potently suppress Nox 1 to 3 and 5, and the goals of this study were to identify how molecular chaperones regulate Nox function. METHODS AND RESULTS: I...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Chen, Feng, Yu, Yanfang, Qian, Jin, Wang, Yusi, Cheng, Bo, Dimitropoulou, Christiana, Patel, Vijay, Chadli, Ahmed, Rudic, R. Dan, Stepp, David W., Catravas, John D., Fulton, David J.R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3499642/
https://ncbi.nlm.nih.gov/pubmed/23023377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.112.300361
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados