The molecular chaperone Hsp90 can negatively regulate the activity of a glucocorticosteroid-dependent promoter

Hsp90, a molecular chaperone required for the functioning of glucocorticosteroid receptor (GR), ensures, by direct interaction, the conformational competence of the steroid-binding pocket. In addition to having this positive function, Hsp90 maintains steroid receptors in an inactive form in the abse...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Kang, Kwang Il, Meng, Xia, Devin-Leclerc, Jocelyne, Bouhouche, Ilham, Chadli, Ahmed, Cadepond, Françoise, Baulieu, Etienne-Emile, Catelli, Maria-Grazia
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1999
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC15481/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9990042/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.4.1439
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