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The molecular chaperone Hsp90 can negatively regulate the activity of a glucocorticosteroid-dependent promoter
Hsp90, a molecular chaperone required for the functioning of glucocorticosteroid receptor (GR), ensures, by direct interaction, the conformational competence of the steroid-binding pocket. In addition to having this positive function, Hsp90 maintains steroid receptors in an inactive form in the abse...
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| Glavni autori: | , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
The National Academy of Sciences
1999
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC15481/ https://ncbi.nlm.nih.gov/pubmed/9990042 |
| Oznake: |
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