The molecular chaperone Hsp90 can negatively regulate the activity of a glucocorticosteroid-dependent promoter

Hsp90, a molecular chaperone required for the functioning of glucocorticosteroid receptor (GR), ensures, by direct interaction, the conformational competence of the steroid-binding pocket. In addition to having this positive function, Hsp90 maintains steroid receptors in an inactive form in the abse...

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Bibliographische Detailangaben
Hauptverfasser: Kang, Kwang Il, Meng, Xia, Devin-Leclerc, Jocelyne, Bouhouche, Ilham, Chadli, Ahmed, Cadepond, Françoise, Baulieu, Etienne-Emile, Catelli, Maria-Grazia
Format: Artigo
Sprache:Inglês
Veröffentlicht: The National Academy of Sciences 1999
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC15481/
https://ncbi.nlm.nih.gov/pubmed/9990042
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