Monocytic and granulocytic myeloid derived suppressor cells differentially regulate spatiotemporal tumour plasticity during metastatic cascade

It is widely accepted that dynamic and reversible tumour cell plasticity is required for metastasis, however, in vivo steps and molecular mechanisms are poorly elucidated. We demonstrate here that monocytic (mMDSC) and granulocytic (gMDSC) subsets of myeloid-derived suppressor cells infiltrate in th...

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Udgivet i:Nat Commun
Main Authors: Ouzounova, Maria, Lee, Eunmi, Piranlioglu, Raziye, El Andaloussi, Abdeljabar, Kolhe, Ravindra, Demirci, Mehmet F., Marasco, Daniela, Asm, Iskander, Chadli, Ahmed, Hassan, Khaled A., Thangaraju, Muthusamy, Zhou, Gang, Arbab, Ali S., Cowell, John K., Korkaya, Hasan
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5384228/
https://ncbi.nlm.nih.gov/pubmed/28382931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms14979
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