Overcoming the challenges of membrane protein crystallography

Por Carpenter, Elisabeth P, Beis, Konstantinos, Cameron, Alexander D, Iwata, So
Publicado em 2008

Insights into outer membrane protein crystallisation

Por NEWSTEAD, SIMON, HOBBS, JEANETTE, JORDAN, DAVINA, CARPENTER, ELISABETH P., IWATA, SO
Publicado em 2008

Mammalian Glucose Transporter Activity Is Dependent upon Anionic and Conical Phospholipids

Por Hresko, Richard C., Kraft, Thomas E., Quigley, Andrew, Carpenter, Elisabeth P., Hruz, Paul W.
Publicado no J Biol Chem (2016)

Asymmetric mechanosensitivity in a eukaryotic ion channel

Por Clausen, Michael V., Jarerattanachat, Viwan, Carpenter, Elisabeth P., Sansom, Mark S. P., Tucker, Stephen J.
Publicado no Proc Natl Acad Sci U S A (2017)

An overview of heavy-atom derivatization of protein crystals

Por Pike, Ashley C. W., Garman, Elspeth F., Krojer, Tobias, von Delft, Frank, Carpenter, Elisabeth P.
Publicado no Acta Crystallogr D Struct Biol (2016)

Polymodal activation of the TREK-2 K2P channel produces structurally distinct open states

Por McClenaghan, Conor, Schewe, Marcus, Aryal, Prafulla, Carpenter, Elisabeth P., Baukrowitz, Thomas, Tucker, Stephen J.
Publicado no J Gen Physiol (2016)

ZMPSTE24 missense mutations that cause progeroid diseases decrease prelamin A cleavage activity and/or protein stability

Por Spear, Eric D., Hsu, Erh-Ting, Nie, Laiyin, Carpenter, Elisabeth P., Hrycyna, Christine A., Michaelis, Susan
Publicado no Dis Model Mech (2018)

Structural basis for the recognition and cleavage of abasic DNA in Neisseria meningitidis

Por Lu, Duo, Silhan, Jan, MacDonald, James T., Carpenter, Elisabeth P., Jensen, Kirsten, Tang, Christoph M., Baldwin, Geoff S., Freemont, Paul S.
Publicado em 2012

Mass spectrometry captures off-target drug binding and provides mechanistic insights into the human metalloprotease ZMPSTE24

Por Mehmood, Shahid, Marcoux, Julien, Gault, Joseph, Quigley, Andrew, Michaelis, Susan, Young, Stephen G., Carpenter, Elisabeth P., Robinson, Carol V.
Publicado no Nat Chem (2016)

MemProtMD: Automated Insertion of Membrane Protein Structures into Explicit Lipid Membranes

Por Stansfeld, Phillip J., Goose, Joseph E., Caffrey, Martin, Carpenter, Elisabeth P., Parker, Joanne L., Newstead, Simon, Sansom, Mark S.P.
Publicado no Structure (2015)

Insights into How Nucleotide-Binding Domains Power ABC Transport

Por Newstead, Simon, Fowler, Philip W., Bilton, Paul, Carpenter, Elisabeth P., Sadler, Peter J., Campopiano, Dominic J., Sansom, Mark S.P., Iwata, So
Publicado em 2009

AP endonuclease paralogues with distinct activities in DNA repair and bacterial pathogenesis

Por Carpenter, Elisabeth P, Corbett, Anne, Thomson, Hellen, Adacha, Jolanta, Jensen, Kirsten, Bergeron, Julien, Kasampalidis, Ioannis, Exley, Rachel, Winterbotham, Megan, Tang, Christoph, Baldwin, Geoff S, Freemont, Paul
Publicado em 2007

Thioredoxin A Active-Site Mutants Form Mixed Disulfide Dimers That Resemble Enzyme–Substrate Reaction Intermediates

Por Kouwen, Thijs R.H.M., Andréll, Juni, Schrijver, Rianne, Dubois, Jean-Yves F., Maher, Megan J., Iwata, So, Carpenter, Elisabeth P., van Dijl, Jan Maarten
Publicado em 2008

Structure of a central stalk subunit F of prokaryotic V-type ATPase/synthase from Thermus thermophilus

Por Makyio, Hisayoshi, Iino, Ryota, Ikeda, Chiyo, Imamura, Hiromi, Tamakoshi, Masatada, Iwata, Momi, Stock, Daniela, Bernal, Ricardo A, Carpenter, Elisabeth P, Yoshida, Masasuke, Yokoyama, Ken, Iwata, So
Publicado em 2005

Atomic resolution insight into host cell recognition by Toxoplasma gondii

Por Blumenschein, Tharin M A, Friedrich, Nikolas, Childs, Robert A, Saouros, Savvas, Carpenter, Elisabeth P, Campanero-Rhodes, Maria A, Simpson, Peter, Chai, Wengang, Koutroukides, Theodoros, Blackman, Michael J, Feizi, Ten, Soldati-Favre, Dominique, Matthews, Stephen
Publicado em 2007

Crystal structure of a prokaryotic homologue of the mammalian oligopeptide–proton symporters, PepT1 and PepT2

Por Newstead, Simon, Drew, David, Cameron, Alexander D, Postis, Vincent L G, Xia, Xiaobing, Fowler, Philip W, Ingram, Jean C, Carpenter, Elisabeth P, Sansom, Mark S P, McPherson, Michael J, Baldwin, Stephen A, Iwata, So
Publicado em 2011

Bilayer-Mediated Structural Transitions Control Mechanosensitivity of the TREK-2 K2P Channel

Por Aryal, Prafulla, Jarerattanachat, Viwan, Clausen, Michael V., Schewe, Marcus, McClenaghan, Conor, Argent, Liam, Conrad, Linus J., Dong, Yin Y., Pike, Ashley C.W., Carpenter, Elisabeth P., Baukrowitz, Thomas, Sansom, Mark S.P., Tucker, Stephen J.
Publicado no Structure (2017)

The SGC beyond structural genomics: redefining the role of 3D structures by coupling genomic stratification with fragment-based discovery

Por Bradley, Anthony R., Echalier, Aude, Fairhead, Michael, Strain-Damerell, Claire, Brennan, Paul, Bullock, Alex N., Burgess-Brown, Nicola A., Carpenter, Elisabeth P., Gileadi, Opher, Marsden, Brian D., Lee, Wen Hwa, Yue, Wyatt, Bountra, Chas, von Delft, Frank
Publicado no Essays Biochem (2017)

K2P channel gating mechanisms revealed by structures of TREK-2 and a complex with Prozac

Por Dong, Yin Yao, Pike, Ashley C.W., Mackenzie, Alexandra, McClenaghan, Conor, Aryal, Prafulla, Dong, Liang, Quigley, Andrew, Grieben, Mariana, Goubin, Solenne, Mukhopadhyay, Shubhashish, Ruda, Gian Filippo, Clausen, Michael V., Cao, Lishuang, Brennan, Paul E., Burgess-Brown, Nicola A., Sansom, Mark S. P., Tucker, Stephen J., Carpenter, Elisabeth P.
Publicado no Science (2015)

Structure and molecular mechanism of a nucleobase-cation-symport-1 family transporter

Por Weyand, Simone, Shimamura, Tatsuro, Yajima, Shunsuke, Suzuki, Shun'ichi, Mirza, Osman, Krusong, Kuakarun, Carpenter, Elisabeth P., Rutherford, Nicholas G., Hadden, Jonathan M., O'Reilly, John, Ma, Pikyee, Saidijam, Massoud, Patching, Simon G., Hope, Ryan J., Norbertczak, Halina T., Roach, Peter C.J., Iwata, So, Henderson, Peter J. F., Cameron, Alexander D.
Publicado em 2008