Structural basis for the recognition and cleavage of abasic DNA in Neisseria meningitidis

Base excision repair (BER) is a highly conserved DNA repair pathway throughout all kingdoms from bacteria to humans. Whereas several enzymes are required to complete the multistep repair process of damaged bases, apurinic-apyrimidic (AP) endonucleases play an essential role in enabling the repair pr...

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Detalhes bibliográficos
Main Authors: Lu, Duo, Silhan, Jan, MacDonald, James T., Carpenter, Elisabeth P., Jensen, Kirsten, Tang, Christoph M., Baldwin, Geoff S., Freemont, Paul S.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3479458/
https://ncbi.nlm.nih.gov/pubmed/23035246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1206563109
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