Specialization of an Exonuclease III family enzyme in the repair of 3′ DNA lesions during base excision repair in the human pathogen Neisseria meningitidis

We have previously demonstrated that the two Exonuclease III (Xth) family members present within the obligate human pathogen Neisseria meningitidis, NApe and NExo, are important for survival under conditions of oxidative stress. Of these, only NApe possesses AP endonuclease activity, while the prima...

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Bibliografiska uppgifter
Huvudupphovsmän: Silhan, Jan, Nagorska, Krzysztofa, Zhao, Qiyuan, Jensen, Kirsten, Freemont, Paul S., Tang, Christoph M., Baldwin, Geoff S.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2012
Ämnen:
Nucleic Acid Enzymes
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3300015/
https://ncbi.nlm.nih.gov/pubmed/22067446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr905
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