Multiscale Simulations Reveal Conserved Patterns of Lipid Interactions with Aquaporins

Por Stansfeld, Phillip J., Jefferys, Elizabeth E., Sansom, Mark S.P.
Publicado em 2013

PIP(2)-Binding Site in Kir Channels: Definition by Multiscale Biomolecular Simulations

Por Stansfeld, Phillip J., Hopkinson, Richard, Ashcroft, Frances M., Sansom, Mark S. P.
Publicado em 2009

Dimerization of the EphA1 Receptor Tyrosine Kinase Transmembrane Domain: Insights into the Mechanism of Receptor Activation

Por Chavent, Matthieu, Chetwynd, Alan P., Stansfeld, Phillip J., Sansom, Mark S. P.
Publicado no Biochemistry (2014)

Balancing Force Field Protein–Lipid Interactions To Capture Transmembrane Helix–Helix Association

Por Domański, Jan, Sansom, Mark S. P., Stansfeld, Phillip J., Best, Robert B.
Publicado no J Chem Theory Comput (2018)

Simulation–based prediction of PIP(2) binding to an ion channel

Por Schmidt, Matthias R., Stansfeld, Phillip J., Tucker, Stephen J., Sansom, Mark S. P.
Publicado no Biochemistry (2012)

Direct Gating of ATP-activated Ion Channels (P2X2 Receptors) by Lipophilic Attachment at the Outer End of the Second Transmembrane Domain

Por Rothwell, Simon W., Stansfeld, Phillip J., Bragg, Laricia, Verkhratsky, Alexej, North, R. Alan
Publicado em 2014

Lipopolysaccharide is Inserted into the Outer Membrane through An Intramembrane Hole, A Lumen Gate, and the Lateral Opening of LptD

Por Gu, Yinghong, Stansfeld, Phillip J., Zeng, Yi, Dong, Haohao, Wang, Wenjian, Dong, Changjiang
Publicado no Structure (2015)

The centriolar protein CPAP G-box: an amyloid fibril in a single domain

Por Cutts, Erin E., Inglis, Alison, Stansfeld, Phillip J., Vakonakis, Ioannis, Hatzopoulos, Georgios N.
Publicado no Biochem Soc Trans (2015)

A Coarse Grained Model for a Lipid Membrane with Physiological Composition and Leaflet Asymmetry

Por Sharma, Satyan, Kim, Brian N., Stansfeld, Phillip J., Sansom, Mark S. P., Lindau, Manfred
Publicado no PLoS One (2015)

Convergence and Sampling in Determining Free Energy Landscapes for Membrane Protein Association

Por Domański, Jan, Hedger, George, Best, Robert B., Stansfeld, Phillip J., Sansom, Mark S. P.
Publicado no J Phys Chem B (2016)

A BEST example of channel structure annotation by molecular simulation

Por Rao, Shanlin, Klesse, Gianni, Stansfeld, Phillip J., Tucker, Stephen J., Sansom, Mark S. P.
Publicado no Channels (Austin) (2017)

Substrate-triggered position switching of TatA and TatB during Tat transport in Escherichia coli

Por Habersetzer, Johann, Moore, Kristoffer, Cherry, Jon, Buchanan, Grant, Stansfeld, Phillip J., Palmer, Tracy
Publicado no Open Biol (2017)

Mechanistic Insight into Human ether-à-go-go-related Gene (hERG) K(+) Channel Deactivation Gating from the Solution Structure of the EAG Domain

Por Muskett, Frederick W., Thouta, Samrat, Thomson, Steven J., Bowen, Alexander, Stansfeld, Phillip J., Mitcheson, John S.
Publicado em 2011

A Leucine Zipper Motif Essential for Gating of Hyperpolarization-activated Channels

Por Wemhöner, Konstantin, Silbernagel, Nicole, Marzian, Stefanie, Netter, Michael F., Rinné, Susanne, Stansfeld, Phillip J., Decher, Niels
Publicado em 2012

A conserved tryptophan at the membrane–water interface acts as a gatekeeper for Kir6.2/SUR1 channels and causes neonatal diabetes when mutated

Por Männikkö, Roope, Stansfeld, Phillip J, Ashcroft, Alexandra S, Hattersley, Andrew T, Sansom, Mark S P, Ellard, Sian, Ashcroft, Frances M
Publicado em 2011

Structural analysis of P. falciparum KAHRP and PfEMP1 complexes with host erythrocyte spectrin suggests a model for cytoadherent knob protrusions

Por Cutts, Erin E., Laasch, Niklas, Reiter, Dirk M., Trenker, Raphael, Slater, Leanne M., Stansfeld, Phillip J., Vakonakis, Ioannis
Publicado no PLoS Pathog (2017)

Structures of monomeric and oligomeric forms of the Toxoplasma gondii perforin-like protein 1

Por Ni, Tao, Williams, Sophie I., Rezelj, Saša, Anderluh, Gregor, Harlos, Karl, Stansfeld, Phillip J., Gilbert, Robert J. C.
Publicado no Sci Adv (2018)

State-independent intracellular access of quaternary ammonium blockers to the pore of TREK-1

Por Rapedius, Markus, Schmidt, Matthias R., Sharma, Chetan, Stansfeld, Phillip J., Sansom, Mark S.P., Baukrowitz, Thomas, Tucker, Stephen J.
Publicado em 2012

Biophysical and Computational Studies of Membrane Penetration by the GRP1 Pleckstrin Homology Domain

Por Lumb, Craig N., He, Ju, Xue, Yi, Stansfeld, Phillip J., Stahelin, Robert V., Kutateladze, Tatiana G., Sansom, Mark S.P.
Publicado em 2011

MemProtMD: Automated Insertion of Membrane Protein Structures into Explicit Lipid Membranes

Por Stansfeld, Phillip J., Goose, Joseph E., Caffrey, Martin, Carpenter, Elisabeth P., Parker, Joanne L., Newstead, Simon, Sansom, Mark S.P.
Publicado no Structure (2015)