Nalaganje...
State-independent intracellular access of quaternary ammonium blockers to the pore of TREK-1
We previously reported that TREK-1 gating by internal pH and pressure occurs close to or within the selectivity filter. These conclusions were based upon kinetic measurements of high-affinity block by quaternary ammonium (QA) ions that appeared to exhibit state-independent accessibility to their bin...
Shranjeno v:
| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Landes Bioscience
2012
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3536734/ https://ncbi.nlm.nih.gov/pubmed/22991046 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/chan.22153 |
| Oznake: |
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