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Access of Quaternary Ammonium Blockers to the Internal Pore of Cyclic Nucleotide-gated Channels: Implications for the Location of the Gate

Cyclic nucleotide-gated (CNG) channels play important roles in the transduction of visual and olfactory information by sensing changes in the intracellular concentration of cyclic nucleotides. We have investigated the interactions between intracellularly applied quaternary ammonium (QA) ions and the...

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Bibliographische Detailangaben
Hauptverfasser: Contreras, Jorge E., Holmgren, Miguel
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2006
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2151523/
https://ncbi.nlm.nih.gov/pubmed/16606688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200509440
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