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Access of Quaternary Ammonium Blockers to the Internal Pore of Cyclic Nucleotide-gated Channels: Implications for the Location of the Gate

Cyclic nucleotide-gated (CNG) channels play important roles in the transduction of visual and olfactory information by sensing changes in the intracellular concentration of cyclic nucleotides. We have investigated the interactions between intracellularly applied quaternary ammonium (QA) ions and the...

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Détails bibliographiques
Auteurs principaux: Contreras, Jorge E., Holmgren, Miguel
Format: Artigo
Langue:Inglês
Publié: The Rockefeller University Press 2006
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2151523/
https://ncbi.nlm.nih.gov/pubmed/16606688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200509440
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