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Cyclic Nucleotide–Gated Channels: Pore Topology Studied through the Accessibility of Reporter Cysteines

In voltage- and cyclic nucleotide–gated ion channels, the amino-acid loop that connects the S5 and S6 transmembrane domains, is a major component of the channel pore. It determines ion selectivity and participates in gating. In the α subunit of cyclic nucleotide–gated channels from bovine rod, the p...

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Detalhes bibliográficos
Main Authors: Becchetti, Andrea, Gamel, Katia, Torre, Vincent
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2229457/
https://ncbi.nlm.nih.gov/pubmed/10469728
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