The pore structure and gating mechanism of K2P channels

Two-pore domain (K2P) potassium channels are important regulators of cellular electrical excitability. However, the structure of these channels and their gating mechanism, in particular the role of the bundle-crossing gate, are not well understood. Here, we report that quaternary ammonium (QA) ions...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Piechotta, Paula L, Rapedius, Markus, Stansfeld, Phillip J, Bollepalli, Murali K, Erhlich, Gunter, Andres-Enguix, Isabelle, Fritzenschaft, Hariolf, Decher, Niels, Sansom, Mark S P, Tucker, Stephen J, Baukrowitz, Thomas
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2011
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3181484/
https://ncbi.nlm.nih.gov/pubmed/21822218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.268
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg