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PIP(2)-Binding Site in Kir Channels: Definition by Multiscale Biomolecular Simulations
[Image: see text] Phosphatidylinositol bisphosphate (PIP(2)) is an activator of mammalian inwardly rectifying potassium (Kir) channels. Multiscale simulations, via a sequential combination of coarse-grained and atomistic molecular dynamics, enabled exploration of the interactions of PIP(2) molecules...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Chemical Society
2009
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2895862/ https://ncbi.nlm.nih.gov/pubmed/19839652 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi9013193 |
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