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Dimerization of the EphA1 Receptor Tyrosine Kinase Transmembrane Domain: Insights into the Mechanism of Receptor Activation

[Image: see text] EphA1 is a receptor tyrosine kinase (RTK) that plays a key role in developmental processes, including guidance of the migration of axons and cells in the nervous system. EphA1, in common with other RTKs, contains an N-terminal extracellular domain, a single transmembrane (TM) α-hel...

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Detalhes bibliográficos
Publicado no:Biochemistry
Main Authors: Chavent, Matthieu, Chetwynd, Alan P., Stansfeld, Phillip J., Sansom, Mark S. P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4298228/
https://ncbi.nlm.nih.gov/pubmed/25286141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi500800x
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