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Structures of the EphA2 Receptor at the Membrane: Role of Lipid Interactions
Ephs are transmembrane receptors that mediate cell-cell signaling. The N-terminal ectodomain binds ligands and enables receptor clustering, which activates the intracellular kinase. Relatively little is known about the function of the membrane-proximal fibronectin domain 2 (FN2) of the ectodomain. M...
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| Pubblicato in: | Structure |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Cell Press
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4744086/ https://ncbi.nlm.nih.gov/pubmed/26724997 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2015.11.008 |
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