Interactions of the EphA2 Kinase Domain with PIPs in Membranes: Implications for Receptor Function

EphA2 is a member of the receptor tyrosine kinase family. Interactions of the cytoplasmic region of EphA2 with the cell membrane are functionally important and yet remain incompletely characterized. Molecular dynamics simulations combined with biochemical studies reveal the interactions of the trans...

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Publicado en:Structure
Main Authors: Chavent, Matthieu, Karia, Dimple, Kalli, Antreas C., Domański, Jan, Duncan, Anna L., Hedger, George, Stansfeld, Phillip J., Seiradake, Elena, Jones, E. Yvonne, Sansom, Mark S.P.
Formato: Artigo
Idioma:Inglês
Publicado: Cell Press 2018
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6039763/
https://ncbi.nlm.nih.gov/pubmed/29887500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2018.05.003
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