A Leucine Zipper Motif Essential for Gating of Hyperpolarization-activated Channels

Hyperpolarization-activated cyclic nucleotide-gated (HCN) channels are pacemakers in cardiac myocytes and neurons. Although their membrane topology closely resembles that of voltage-gated K(+) channels, the mechanism of their unique gating behavior in response to hyperpolarization is still poorly un...

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Bibliografiske detaljer
Main Authors: Wemhöner, Konstantin, Silbernagel, Nicole, Marzian, Stefanie, Netter, Michael F., Rinné, Susanne, Stansfeld, Phillip J., Decher, Niels
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2012
Fag:
Molecular Biophysics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3504729/
https://ncbi.nlm.nih.gov/pubmed/23048023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.378513
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