Biophysical and Computational Studies of Membrane Penetration by the GRP1 Pleckstrin Homology Domain

The pleckstrin homology (PH) domain of the general receptor for phosphoinositides 1 (GRP1) exhibits specific, high-affinity, reversible binding to phosphatidylinositol (3,4,5)-trisphosphate (PI(3,4,5)P(3)) at the plasma membrane, but the nature and extent of the interaction between this bound comple...

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Autores principales: Lumb, Craig N., He, Ju, Xue, Yi, Stansfeld, Phillip J., Stahelin, Robert V., Kutateladze, Tatiana G., Sansom, Mark S.P.
Formato: Artigo
Lenguaje:Inglês
Publicado: Cell Press 2011
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3173609/
https://ncbi.nlm.nih.gov/pubmed/21893292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2011.04.010
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