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Structure and lipid-binding properties of the kindlin-3 pleckstrin homology domain
Kindlins co-activate integrins alongside talin. They possess, like talin, a FERM domain (4.1-erythrin–radixin–moiesin domain) comprising F0–F3 subdomains, but with a pleckstrin homology (PH) domain inserted in the F2 subdomain that enables membrane association. We present the crystal structure of mu...
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Publicado no: | Biochem J |
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Main Authors: | , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Portland Press Ltd.
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5290484/ https://ncbi.nlm.nih.gov/pubmed/27974389 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BCJ20160791 |
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