Structure and lipid-binding properties of the kindlin-3 pleckstrin homology domain

Kindlins co-activate integrins alongside talin. They possess, like talin, a FERM domain (4.1-erythrin–radixin–moiesin domain) comprising F0–F3 subdomains, but with a pleckstrin homology (PH) domain inserted in the F2 subdomain that enables membrane association. We present the crystal structure of mu...

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Detalhes bibliográficos
Publicado no:Biochem J
Main Authors: Ni, Tao, Kalli, Antreas C., Naughton, Fiona B., Yates, Luke A., Naneh, Omar, Kozorog, Mirijam, Anderluh, Gregor, Sansom, Mark S.P., Gilbert, Robert J.C.
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2017
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5290484/
https://ncbi.nlm.nih.gov/pubmed/27974389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BCJ20160791
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