Molecular Basis of Phosphatidylinositol 4-Phosphate and ARF1 GTPase Recognition by the FAPP1 Pleckstrin Homology (PH) Domain

Four-phosphate-adaptor protein 1 (FAPP1) regulates secretory transport from the trans-Golgi network (TGN) to the plasma membrane. FAPP1 is recruited to the Golgi through binding of its pleckstrin homology (PH) domain to phosphatidylinositol 4-phosphate (PtdIns(4)P) and a small GTPase ADP-ribosylatio...

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Detalhes bibliográficos
Main Authors: He, Ju, Scott, Jordan L., Heroux, Annie, Roy, Siddhartha, Lenoir, Marc, Overduin, Michael, Stahelin, Robert V., Kutateladze, Tatiana G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Lipids
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3099681/
https://ncbi.nlm.nih.gov/pubmed/21454700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.233015
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