Lipopolysaccharide is Inserted into the Outer Membrane through An Intramembrane Hole, A Lumen Gate, and the Lateral Opening of LptD

Lipopolysaccharide (LPS) is essential for the vitality of most Gram-negative bacteria and plays an important role in bacterial multidrug resistance. The LptD/E translocon inserts LPS into the outer leaflet, the mechanism of which is poorly understood. Here, we report mutagenesis, functional assays,...

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Vydáno v:Structure
Hlavní autoři: Gu, Yinghong, Stansfeld, Phillip J., Zeng, Yi, Dong, Haohao, Wang, Wenjian, Dong, Changjiang
Médium: Artigo
Jazyk:Inglês
Vydáno: Cell Press 2015
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4353691/
https://ncbi.nlm.nih.gov/pubmed/25684578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2015.01.001
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