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Polymodal activation of the TREK-2 K2P channel produces structurally distinct open states
The TREK subfamily of two-pore domain (K2P) K(+) channels exhibit polymodal gating by a wide range of physical and chemical stimuli. Crystal structures now exist for these channels in two main states referred to as the “up” and “down” conformations. However, recent studies have resulted in contradic...
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| Publicado no: | J Gen Physiol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4886281/ https://ncbi.nlm.nih.gov/pubmed/27241700 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201611601 |
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