Crystal structure of a prokaryotic homologue of the mammalian oligopeptide–proton symporters, PepT1 and PepT2

PepT1 and PepT2 are major facilitator superfamily (MFS) transporters that utilize a proton gradient to drive the uptake of di- and tri-peptides in the small intestine and kidney, respectively. They are the major routes by which we absorb dietary nitrogen and many orally administered drugs. Here, we...

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Main Authors: Newstead, Simon, Drew, David, Cameron, Alexander D, Postis, Vincent L G, Xia, Xiaobing, Fowler, Philip W, Ingram, Jean C, Carpenter, Elisabeth P, Sansom, Mark S P, McPherson, Michael J, Baldwin, Stephen A, Iwata, So
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3025455/
https://ncbi.nlm.nih.gov/pubmed/21131908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2010.309
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