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Gating Topology of the Proton-Coupled Oligopeptide Symporters

Proton-coupled oligopeptide transporters belong to the major facilitator superfamily (MFS) of membrane transporters. Recent crystal structures suggest the MFS fold facilitates transport through rearrangement of their two six-helix bundles around a central ligand binding site; how this is achieved, h...

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Publicado en:Structure
Main Authors: Fowler, Philip W., Orwick-Rydmark, Marcella, Radestock, Sebastian, Solcan, Nicolae, Dijkman, Patricia M., Lyons, Joseph A., Kwok, Jane, Caffrey, Martin, Watts, Anthony, Forrest, Lucy R., Newstead, Simon
Formato: Artigo
Idioma:Inglês
Publicado: Cell Press 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4321885/
https://ncbi.nlm.nih.gov/pubmed/25651061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2014.12.012
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