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Structural basis for polyspecificity in the POT family of proton-coupled oligopeptide transporters
An enigma in the field of peptide transport is the structural basis for ligand promiscuity, as exemplified by PepT1, the mammalian plasma membrane peptide transporter. Here, we present crystal structures of di- and tripeptide-bound complexes of a bacterial homologue of PepT1, which reveal at least t...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BlackWell Publishing Ltd
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4149780/ https://ncbi.nlm.nih.gov/pubmed/24916388 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201338403 |
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