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Structural basis for polyspecificity in the POT family of proton-coupled oligopeptide transporters
An enigma in the field of peptide transport is the structural basis for ligand promiscuity, as exemplified by PepT1, the mammalian plasma membrane peptide transporter. Here, we present crystal structures of di- and tripeptide-bound complexes of a bacterial homologue of PepT1, which reveal at least t...
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| 主要な著者: | , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
BlackWell Publishing Ltd
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4149780/ https://ncbi.nlm.nih.gov/pubmed/24916388 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201338403 |
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