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Accurate Prediction of Ligand Affinities for a Proton-Dependent Oligopeptide Transporter
Membrane transporters are critical modulators of drug pharmacokinetics, efficacy, and safety. One example is the proton-dependent oligopeptide transporter PepT1, also known as SLC15A1, which is responsible for the uptake of the β-lactam antibiotics and various peptide-based prodrugs. In this study,...
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| Pubblicato in: | Cell Chem Biol |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Cell Press
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4760754/ https://ncbi.nlm.nih.gov/pubmed/27028887 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2015.11.015 |
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