Structural basis for polyspecificity in the POT family of proton-coupled oligopeptide transporters

An enigma in the field of peptide transport is the structural basis for ligand promiscuity, as exemplified by PepT1, the mammalian plasma membrane peptide transporter. Here, we present crystal structures of di- and tripeptide-bound complexes of a bacterial homologue of PepT1, which reveal at least t...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Lyons, Joseph A, Parker, Joanne L, Solcan, Nicolae, Brinth, Alette, Li, Dianfan, Shah, Syed TA, Caffrey, Martin, Newstead, Simon
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BlackWell Publishing Ltd 2014
Gaiak:
Scientific Reports
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4149780/
https://ncbi.nlm.nih.gov/pubmed/24916388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201338403
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