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Residues R282 and D341 act as electrostatic gates in the proton-dependent oligopeptide transporter PepT1
The effects of mutations in the charge pair residues Arg282 and Asp341 of the rabbit oligopeptide transporter PepT1 have been studied using electrophysiology in mRNA-injected Xenopus oocytes. Substitution of Arg282 with neutral or negatively charged residues produced a shift towards more positive po...
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| Hauptverfasser: | , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Blackwell Science Inc
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3055539/ https://ncbi.nlm.nih.gov/pubmed/21115649 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2010.200469 |
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