Residues R282 and D341 act as electrostatic gates in the proton-dependent oligopeptide transporter PepT1

The effects of mutations in the charge pair residues Arg282 and Asp341 of the rabbit oligopeptide transporter PepT1 have been studied using electrophysiology in mRNA-injected Xenopus oocytes. Substitution of Arg282 with neutral or negatively charged residues produced a shift towards more positive po...

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Hlavní autoři: Bossi, Elena, Renna, Maria Daniela, Sangaletti, Rachele, D’Antoni, Francesca, Cherubino, Francesca, Kottra, Gabor, Peres, Antonio
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Science Inc 2011
Témata:
Molecular and Cellular
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3055539/
https://ncbi.nlm.nih.gov/pubmed/21115649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2010.200469
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