The SGC beyond structural genomics: redefining the role of 3D structures by coupling genomic stratification with fragment-based discovery

The ongoing explosion in genomics data has long since outpaced the capacity of conventional biochemical methodology to verify the large number of hypotheses that emerge from the analysis of such data. In contrast, it is still a gold-standard for early phenotypic validation towards small-molecule dru...

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Detalhes bibliográficos
Publicado no:Essays Biochem
Main Authors: Bradley, Anthony R., Echalier, Aude, Fairhead, Michael, Strain-Damerell, Claire, Brennan, Paul, Bullock, Alex N., Burgess-Brown, Nicola A., Carpenter, Elisabeth P., Gileadi, Opher, Marsden, Brian D., Lee, Wen Hwa, Yue, Wyatt, Bountra, Chas, von Delft, Frank
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2017
Assuntos:
Review Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5869235/
https://ncbi.nlm.nih.gov/pubmed/29118096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/EBC20170051
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