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Crystal Structures of the Catalytic Domain of Human Soluble Guanylate Cyclase

Soluble guanylate cyclase (sGC) catalyses the synthesis of cyclic GMP in response to nitric oxide. The enzyme is a heterodimer of homologous α and β subunits, each of which is composed of multiple domains. We present here crystal structures of a heterodimer of the catalytic domains of the α and β su...

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Detalhes bibliográficos
Main Authors: Allerston, Charles K., von Delft, Frank, Gileadi, Opher
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3591389/
https://ncbi.nlm.nih.gov/pubmed/23505436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0057644
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