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The SGC beyond structural genomics: redefining the role of 3D structures by coupling genomic stratification with fragment-based discovery
The ongoing explosion in genomics data has long since outpaced the capacity of conventional biochemical methodology to verify the large number of hypotheses that emerge from the analysis of such data. In contrast, it is still a gold-standard for early phenotypic validation towards small-molecule dru...
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| Pubblicato in: | Essays Biochem |
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| Autori principali: | , , , , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Portland Press Ltd.
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5869235/ https://ncbi.nlm.nih.gov/pubmed/29118096 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/EBC20170051 |
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