Human UGT1A8 and UGT1A10 mRNA Are Expressed In Primary Human Hepatocytes

Por Li, Xin, Bratton, Stacie, Radominska-Pandya, Anna
Publicado em 2007

Effect of Retinoids on UDP-Glucuronosyltransferase 2B7 mRNA Expression in Caco-2 Cells

Por Lu, Yuan, Bratton, Stacie, Heydel, Jean-Marie, Radominska-Pandya, Anna
Publicado em 2008

The crystal structure of human UDP-glucuronosyltransferase 2B7 C-terminal end is the first mammalian UGT target to be revealed: the significance for human UGTs from both the 1A and...

Por Radominska-Pandya, Anna, Bratton, Stacie M., Redinbo, Matthew R., Miley, Michael J.
Publicado em 2010

Role of Human UDP-Glucuronosyltransferases in the Biotransformation of the Triazoloacridinone and Imidazoacridinone Antitumor Agents C-1305 and C-1311: Highly Selective Substrates...

Por Fedejko-Kap, Barbara, Bratton, Stacie M., Finel, Moshe, Radominska-Pandya, Anna, Mazerska, Zofia
Publicado em 2012

LITHOCHOLIC ACID DECREASES EXPRESSION OF UGT2B7 IN CACO-2 CELLS: A POTENTIAL ROLE FOR A NEGATIVE FARNESOID X RECEPTOR RESPONSE ELEMENT

Por Lu, Yuan, Heydel, Jean-Marie, Li, Xin, Bratton, Stacie, Lindblom, Tim, Radominska-Pandya, Anna
Publicado em 2005

PHENYLALANINE(90) AND PHENYLALANINE(93) ARE CRUCIAL AMINO ACIDS WITHIN THE ESTROGEN BINDING SITE OF THE HUMAN UDP-GLUCURONOSYLTRANSFERASE 1A10

Por Starlard-Davenport, Athena, Xiong, Yan, Bratton, Stacie, Gallus-Zawada, Anna, Finel, Moshe, Radominska-Pandya, Anna
Publicado em 2006

Crystal Structure of the Cofactor-Binding Domain of the Human Phase II Drug-Metabolism Enzyme UDP-Glucuronosyltransferase 2B7

Por Miley, Michael J., Zielinska, Agnieszka K., Keenan, Jeffrey E., Bratton, Stacie M., Radominska-Pandya, Anna, Redinbo, Matthew R.
Publicado em 2007

Analysis of R- and S-Hydroxywarfarin Glucuronidation Catalyzed by Human Liver Microsomes and Recombinant UDP-Glucuronosyltransferases

Por Bratton, Stacie M., Mosher, Carrie M., Khallouki, Farid, Finel, Moshe, Court, Michael H., Moran, Jeffery H., Radominska-Pandya, Anna
Publicado em 2012

Novel Resveratrol-Based Substrates for Human Hepatic, Renal, and Intestinal UDP-Glucuronosyltransferases

Por Greer, Aleksandra K., Madadi, Nikhil R., Bratton, Stacie M., Eddy, Sarah D., Mazerska, Zofia, Hendrickson, Howard P., Crooks, Peter A., Radominska-Pandya, Anna
Publicado em 2014

Identification of Hydroxywarfarin Binding Site in Human UDP Glucuronosyltransferase 1A10: Phenylalanine(90) Is Crucial for the Glucuronidation of 6- and 7-Hydroxywarfarin but Not 8...

Por Miller, Grover P., Lichti, Cheryl F., Zielinska, Agnieszka K., Mazur, Anna, Bratton, Stacie M., Gallus-Zawada, Anna, Finel, Moshe, Moran, Jeffery H., Radominska-Pandya, Anna
Publicado em 2008

Ethylenediamine functionalized-single-walled nanotube (f-SWNT)-assisted in vitro delivery of the oncogene suppressor p53 gene to breast cancer MCF-7 cells

Por Karmakar, Alokita, Bratton, Stacie M, Dervishi, Enkeleda, Ghosh, Anindya, Mahmood, Meena, Xu, Yang, Saeed, Lamya Mohammed, Mustafa, Thikra, Casciano, Dan, Radominska-Pandya, Anna, Biris, Alexandru S
Publicado em 2011

CB1 and CB2 Receptors are Novel Molecular Targets for Tamoxifen and 4OH-Tamoxifen

Por Prather, Paul L., FrancisDevaraj, FeAna, Dates, Centdrika R., Greer, Aleksandra K., Bratton, Stacie M., Ford, Benjamin M., Franks, Lirit N., Radominska-Pandya, Anna
Publicado em 2013

Conjugation of Synthetic Cannabinoids JWH-018 and JWH-073, Metabolites by Human UDP-Glucuronosyltransferases

Por Chimalakonda, Krishna C., Bratton, Stacie M., Le, Vi-Huyen, Yiew, Kan Hui, Dineva, Anna, Moran, Cindy L., James, Laura P., Moran, Jeffery H., Radominska-Pandya, Anna
Publicado em 2011

A Potential Role for Human UDP-Glucuronosyltransferase 1A4 Promoter Single Nucleotide Polymorphisms in the Pharmacogenomics of Tamoxifen and Its Derivatives

Por Greer, Aleksandra K., Dates, Centdrika R., Starlard-Davenport, Athena, Edavana, Vineetha K., Bratton, Stacie M., Dhakal, Ishwori B., Finel, Moshe, Kadlubar, Susan A., Radominska-Pandya, Anna
Publicado em 2014

The First Aspartic Acid of the DQxD Motif for Human UDP-Glucuronosyltransferase 1A10 Interacts with UDP-Glucuronic Acid during Catalysis

Por Xiong, Yan, Patana, Anne-Sisko, Miley, Michael J., Zielinska, Agnieszka K., Bratton, Stacie M., Miller, Grover P., Goldman, Adrian, Finel, Moshe, Redinbo, Matt R., Radominska-Pandya, Anna
Publicado em 2007

Glucuronidation of Monohydroxylated Warfarin Metabolites by Human Liver Microsomes and Human Recombinant UDP-Glucuronosyltransferases

Por Zielinska, Agnieszka, Lichti, Cheryl F., Bratton, Stacie, Mitchell, Neil C., Gallus-Zawada, Anna, Le, Vi-Huyen, Finel, Moshe, Miller, Grover P., Radominska-Pandya, Anna, Moran, Jeffery H.
Publicado em 2007

Characterization of Human Hepatic and Extrahepatic UDP-Glucuronosyltransferase Enzymes Involved in the Metabolism of Classic Cannabinoids

Por Mazur, Anna, Lichti, Cheryl F., Prather, Paul L., Zielinska, Agnieszka K., Bratton, Stacie M., Gallus-Zawada, Anna, Finel, Moshe, Miller, Grover P., Radomińska-Pandya, Anna, Moran, Jeffery H.
Publicado em 2009

Human UDP-Glucuronosyltransferases: Effects of altered expression in breast and pancreatic cancer cell lines

Por Dates, Centdrika R, Fahmi, Tariq, Pyrek, Sebastian J, Yao-Borengasser, Aiwei, Borowa-Mazgaj, Barbara, Bratton, Stacie M, Kadlubar, Susan A, Mackenzie, Peter I, Haun, Randy S, Radominska-Pandya, Anna
Publicado no Cancer Biol Ther (2015)

Single-walled carbon nanotube and graphene nanodelivery of gambogic acid increases its cytotoxicity in breast and pancreatic cancer cells

Por Saeed, Lamya M, Mahmood, Meena, Pyrek, Sebastian J., Fahmi, Tariq, Xu, Yang, Mustafa, Thikra, Nima, Zeid A., Bratton, Stacie M., Casciano, Dan, Dervishi, Enkeleda, Radominska-Pandya, Anna, Biris, Alexandru S.
Publicado no J Appl Toxicol (2014)

Natural prenylated resveratrol analogs arachidin-1 and -3 demonstrate improved glucuronidation profiles and have affinity for cannabinoid receptors

Por Brents, Lisa K., Medina-Bolivar, Fabricio, Seely, Kathryn A., Nair, Vipin, Bratton, Stacie M., Ñopo-Olazabal, Luis, Patel, Ronak Y., Liu, Haining, Doerksen, Robert J., Prather, Paul L., Radominska-Pandya, Anna
Publicado em 2011