Ethylenediamine functionalized-single-walled nanotube (f-SWNT)-assisted in vitro delivery of the oncogene suppressor p53 gene to breast cancer MCF-7 cells

A gene delivery concept based on ethylenediamine-functionalized single-walled carbon nanotubes (f-SWCNTs) using the oncogene suppressor p53 gene as a model gene was successfully tested in vitro in MCF-7 breast cancer cells. The f-SWCNTs-p53 complexes were introduced into the cell medium at a concent...

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Autori principali: Karmakar, Alokita, Bratton, Stacie M, Dervishi, Enkeleda, Ghosh, Anindya, Mahmood, Meena, Xu, Yang, Saeed, Lamya Mohammed, Mustafa, Thikra, Casciano, Dan, Radominska-Pandya, Anna, Biris, Alexandru S
Natura: Artigo
Lingua:Inglês
Pubblicazione: Dove Medical Press 2011
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Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3124390/
https://ncbi.nlm.nih.gov/pubmed/21720516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S17684
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