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Crystal Structure of the Cofactor-Binding Domain of the Human Phase II Drug-Metabolism Enzyme UDP-Glucuronosyltransferase 2B7

Human UDP-glucuronosyltransferases (UGT) are the dominant phase II conjugative drug metabolism enzymes that also play a central role in the processing of a range of endobiotic compounds. UGTs catalyze the covalent addition of glucuronic acid sugar moieties to a host of therapeutics and environmental...

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Sonraí Bibleagrafaíochta
Main Authors: Miley, Michael J., Zielinska, Agnieszka K., Keenan, Jeffrey E., Bratton, Stacie M., Radominska-Pandya, Anna, Redinbo, Matthew R.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2007
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1976284/
https://ncbi.nlm.nih.gov/pubmed/17442341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2007.03.066
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