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The crystal structure of human UDP-glucuronosyltransferase 2B7 C-terminal end is the first mammalian UGT target to be revealed: the significance for human UGTs from both the 1A and 2B families

Human UDP-glucuronosyltransferases (EC 2.4.1.17) (UGTs) are major phase II metabolism enzymes that detoxify a multitude of endo- and xenobiotics through the covalent addition of a glucuronic acid moiety. UGTs are promiscuous enzymes that regulate the levels of numerous important endobiotics in a ran...

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Detaylı Bibliyografya
Asıl Yazarlar: Radominska-Pandya, Anna, Bratton, Stacie M., Redinbo, Matthew R., Miley, Michael J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2010
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3192453/
https://ncbi.nlm.nih.gov/pubmed/19821783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/03602530903209049
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