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Novel Resveratrol-Based Substrates for Human Hepatic, Renal, and Intestinal UDP-Glucuronosyltransferases

[Image: see text] Trans-Resveratrol (tRes) has been shown to have powerful antioxidant, anti-inflammatory, anticarcinogenic, and antiaging properties; however, its use as a therapeutic agent is limited by its rapid metabolism into its conjugated forms by UDP-glucuronosyltransferases (UGTs). The aim...

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Detalhes bibliográficos
Main Authors: Greer, Aleksandra K., Madadi, Nikhil R., Bratton, Stacie M., Eddy, Sarah D., Mazerska, Zofia, Hendrickson, Howard P., Crooks, Peter A., Radominska-Pandya, Anna
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4002122/
https://ncbi.nlm.nih.gov/pubmed/24571610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx400408x
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